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Naoki Harada Selected Research

Glyceraldehyde-3-Phosphate Dehydrogenases (GAPD)

1/2017Glyceraldehyde-3-phosphate Dehydrogenase (GAPDH) Aggregation Causes Mitochondrial Dysfunction during Oxidative Stress-induced Cell Death.
10/2015Glyceraldehyde-3-phosphate Dehydrogenase Aggregates Accelerate Amyloid-β Amyloidogenesis in Alzheimer Disease.
5/2011Up-regulation of glyceraldehyde-3-phosphate dehydrogenase gene expression by HIF-1 activity depending on Sp1 in hypoxic breast cancer cells.
8/2007Glyceraldehyde-3-phosphate dehydrogenase enhances transcriptional activity of androgen receptor in prostate cancer cells.

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Naoki Harada Research Topics

Disease

25Neoplasms (Cancer)
06/2022 - 08/2004
10Hypoxia (Hypoxemia)
01/2016 - 10/2008
10Prostatic Neoplasms (Prostate Cancer)
10/2015 - 08/2007
9Breast Neoplasms (Breast Cancer)
01/2022 - 05/2011
7Infections
07/2015 - 01/2007
5Muscular Atrophy (Muscle Atrophy)
01/2021 - 04/2013
5Hypertrophy
01/2020 - 01/2015
5Chronic Hepatitis C
03/2016 - 04/2013
5Graft vs Host Disease (Graft-Versus-Host Disease)
01/2011 - 10/2007
4Obesity
07/2022 - 11/2016
4Non-alcoholic Fatty Liver Disease
12/2020 - 01/2015
4Stomach Neoplasms (Stomach Cancer)
01/2020 - 09/2013
4Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2020 - 02/2014
4Type 2 Diabetes Mellitus (MODY)
11/2019 - 06/2015
4Fibrosis (Cirrhosis)
07/2015 - 04/2013
3Inflammation (Inflammations)
07/2022 - 01/2020
3Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular)
06/2022 - 01/2021
3Non-Hodgkin Lymphoma (Lymphosarcoma)
06/2022 - 01/2021
3Lung Neoplasms (Lung Cancer)
01/2022 - 01/2014
3Hyperglycemia
11/2020 - 01/2017
3Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
07/2015 - 10/2008
3Hepatocellular Carcinoma (Hepatoma)
07/2015 - 04/2013
2Abdominal Obesity
11/2020 - 03/2016
2Metabolic Diseases (Metabolic Disease)
11/2020 - 01/2020
2Atrophy
07/2020 - 04/2013
2Hypogonadism (Hypergonadotropic Hypogonadism)
01/2020 - 03/2016
2Glucose Intolerance
11/2019 - 01/2018
2Body Weight (Weight, Body)
11/2019 - 01/2015
2Sarcoma (Soft Tissue Sarcoma)
04/2019 - 02/2014
2Cardiovascular Diseases (Cardiovascular Disease)
10/2018 - 11/2016
2Hemorrhage
05/2017 - 01/2007
2Mitochondrial Diseases (Mitochondrial Disease)
01/2017 - 10/2015
2Primary Myelofibrosis (Myelosclerosis)
01/2016 - 05/2007
2Virus Diseases (Viral Diseases)
07/2015 - 11/2005
2Anemia
03/2015 - 05/2007
2Neutropenia
02/2013 - 07/2012
2Cytomegalovirus Infections (Inclusion Disease)
07/2012 - 03/2009
2Carcinoma (Carcinomatosis)
06/2012 - 02/2011
2Aspergillosis
07/2011 - 06/2010
2Pain (Aches)
11/2010 - 10/2006

Drug/Important Bio-Agent (IBA)

12Androgen Receptors (Androgen Receptor)IBA
11/2020 - 08/2007
11AndrogensIBA
11/2020 - 01/2011
10Proteins (Proteins, Gene)FDA Link
01/2020 - 01/2002
8ErbB Receptors (EGF Receptor)IBA
01/2020 - 01/2014
7Messenger RNA (mRNA)IBA
07/2022 - 11/2005
7LigandsIBA
09/2012 - 08/2007
6Trastuzumab (Herceptin)FDA Link
11/2020 - 09/2013
6Ribavirin (Virazole)FDA LinkGeneric
03/2016 - 10/2008
6DNA (Deoxyribonucleic Acid)IBA
07/2015 - 01/2006
5human ERBB2 proteinIBA
11/2020 - 09/2013
5Testosterone (Sustanon)FDA Link
10/2018 - 08/2002
5InterferonsIBA
03/2016 - 04/2013
4Biomarkers (Surrogate Marker)IBA
01/2022 - 01/2011
4Pharmaceutical PreparationsIBA
01/2020 - 02/2016
4Glyceraldehyde-3-Phosphate Dehydrogenases (GAPD)IBA
01/2017 - 08/2007
4Transcription Factors (Transcription Factor)IBA
01/2016 - 03/2008
4ResveratrolIBA
01/2014 - 12/2007
3obinutuzumabIBA
06/2022 - 01/2021
3Tyrosine Kinase InhibitorsIBA
01/2022 - 01/2014
3alectinibIBA
01/2022 - 03/2016
3Anti-Bacterial Agents (Antibiotics)IBA
03/2021 - 06/2010
3Ado-Trastuzumab EmtansineIBA
11/2020 - 09/2013
3pertuzumabIBA
11/2020 - 09/2013
3Carotenoids (Carotene)IBA
01/2020 - 04/2013
3Glucose (Dextrose)FDA LinkGeneric
01/2017 - 01/2015
3UbiquitinIBA
10/2015 - 04/2013
3Antiviral Agents (Antivirals)IBA
03/2015 - 04/2013
3Proteasome Endopeptidase Complex (Proteasome)IBA
01/2014 - 04/2013
3Adrenal Cortex Hormones (Corticosteroids)IBA
01/2010 - 10/2008
2oleylamide (oleamide)IBA
07/2022 - 01/2021
2Anaplastic Lymphoma KinaseIBA
01/2022 - 04/2019
2G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA
01/2020 - 01/2017
2Ethanol (Ethyl Alcohol)IBA
01/2020 - 11/2019
2Insulin (Novolin)FDA Link
11/2019 - 01/2017
2Doxorubicin (Adriamycin)FDA LinkGeneric
06/2018 - 01/2014
2LactoferrinIBA
01/2018 - 12/2017
2GlucocorticoidsIBA
01/2018 - 06/2015
2Ubiquitin-Specific ProteasesIBA
11/2017 - 06/2015
2Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA
10/2017 - 07/2013
2Small Interfering RNA (siRNA)IBA
10/2015 - 01/2011
2EnzymesIBA
09/2015 - 02/2014
2Oxaliplatin (Eloxatin)FDA LinkGeneric
09/2015 - 02/2013
2Dihydrotestosterone (Androstanolone)IBA
01/2015 - 01/2011
2Aspartate Aminotransferases (Aspartate Transaminase)IBA
07/2014 - 02/2014
2Proteasome InhibitorsIBA
01/2014 - 01/2014
2CateninsIBA
01/2014 - 09/2012
2RO5126766IBA
09/2013 - 07/2013
2Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
09/2013 - 07/2013
2ValganciclovirFDA Link
07/2012 - 03/2009
2Granulocyte Colony-Stimulating Factor (G-CSF)IBA
07/2012 - 02/2011
2Hormones (Hormone)IBA
06/2012 - 01/2011
2Calcineurin InhibitorsIBA
11/2010 - 10/2006

Therapy/Procedure

22Therapeutics
01/2022 - 01/2002
7Castration
01/2018 - 01/2011
7Hematopoietic Stem Cell Transplantation
03/2012 - 10/2007
6Drug Therapy (Chemotherapy)
01/2021 - 04/2007
6Transplantation
01/2016 - 01/2007
3Retreatment
06/2022 - 01/2021
3Bone Marrow Transplantation (Transplantation, Bone Marrow)
01/2009 - 10/2006
2Stem Cell Transplantation
03/2012 - 07/2011